{"id":1572,"date":"2021-01-16T17:59:14","date_gmt":"2021-01-16T15:59:14","guid":{"rendered":"http:\/\/journals.khnu.km.ua\/vestnik\/?p=1572"},"modified":"2021-05-17T14:44:51","modified_gmt":"2021-05-17T11:44:51","slug":"%d0%bc%d0%b5%d1%82%d0%be%d0%b4%d0%be%d0%bb%d0%be%d0%b3%d1%96%d1%8f-%d0%bf%d1%96%d0%b4%d0%b3%d0%be%d1%82%d0%be%d0%b2%d0%ba%d0%b8-%d0%bf%d1%80%d0%be%d0%b1-%d0%b2-%d0%ba%d0%be%d0%bd%d1%82%d1%80%d0%be","status":"publish","type":"post","link":"https:\/\/journals.khnu.km.ua\/vestnik\/?p=1572","title":{"rendered":"\u041c\u0435\u0442\u043e\u0434\u043e\u043b\u043e\u0433\u0456\u044f \u043f\u0456\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0438 \u043f\u0440\u043e\u0431 \u0432 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0456 \u0432\u043c\u0456\u0441\u0442\u0443 \u043a\u0441\u0435\u043d\u043e\u0431\u0456\u043e\u0442\u0438\u043a\u0456\u0432"},"content":{"rendered":"

\u041c\u0415\u0422\u041e\u0414\u041e\u041b\u041e\u0413\u0406\u042f \u041f\u0406\u0414\u0413\u041e\u0422\u041e\u0412\u041a\u0418 \u041f\u0420\u041e\u0411 \u0412 \u041a\u041e\u041d\u0422\u0420\u041e\u041b\u0406 \u0412\u041c\u0406\u0421\u0422\u0423 \u041a\u0421\u0415\u041d\u041e\u0411\u0406\u041e\u0422\u0418\u041a\u0406\u0412<\/p>\n

METHODOLOGY OF SAMPLE PREPARATION FOR XENOBIOTICS CONTENT ANALYSIS<\/p>\n

<\/a> \u0421\u0442\u043e\u0440\u0456\u043d\u043a\u0438: 7-11. \u041d\u043e\u043c\u0435\u0440: \u21164, 2019 (275)<\/strong>
\n\u0410\u0432\u0442\u043e\u0440\u0438: <\/strong>
\n\u041d.\u042e. \u0413\u0420\u0418\u0411\u041e\u0412\u0410, \u041e.\u042e. \u041a\u0423\u0420\u0421\u0415\u041d\u041a\u041e, \u041e.\u0406. \u0425\u0418\u0416\u0410\u041d, \u041b.\u041e. \u041a\u041e\u0412\u0428\u0423\u041d
\n\u041d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442 \u0431\u0456\u043e\u0440\u0435\u0441\u0443\u0440\u0441\u0456\u0432 \u0442\u0430 \u043f\u0440\u0438\u0440\u043e\u0434\u043e\u043a\u043e\u0440\u0438\u0441\u0442\u0443\u0432\u0430\u043d\u043d\u044f \u0423\u043a\u0440\u0430\u0457\u043d\u0438, \u041d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u043c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442 \u0456\u043c\u0435\u043d\u0456 \u041e.\u041e. \u0411\u043e\u0433\u043e\u043c\u043e\u043b\u044c\u0446\u044f
\nN.Y. HRYBOVA, O.Y. KURSENKO, O.I. KHYZHAN, L.O. KOVSHUN
\nNational University of Life and Environmental Sciences of Ukraine, Bogomolets National Medical University
\nDOI:<\/strong> https:\/\/www.doi.org\/10.31891\/2307-5732-2019-275-4-7-11<\/a>
\n\u0420\u0435\u0446\u0435\u043d\u0437\u0456\u044f\/Peer review :<\/strong> 29.05.2019 \u0440.
\n\u041d\u0430\u0434\u0440\u0443\u043a\u043e\u0432\u0430\u043d\u0430\/Printed :<\/strong> 17.07.2019 \u0440.<\/p>\n

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\n\u041a\u043b\u044e\u0447\u043e\u0432\u0456 \u0441\u043b\u043e\u0432\u0430:<\/strong> \u043f\u043e\u043a\u0430\u0437\u043d\u0438\u043a\u0438 \u0431\u0435\u0437\u043f\u0435\u0447\u043d\u043e\u0441\u0442\u0456, \u043a\u0441\u0435\u043d\u043e\u0431\u0456\u043e\u0442\u0438\u043a\u0438, \u043f\u0435\u0441\u0442\u0438\u0446\u0438\u0434\u0438, \u043f\u043e\u0445\u0456\u0434\u043d\u0456 \u0431\u0435\u043d\u0437\u0456\u043c\u0456\u0434\u0430\u0437\u043e\u043b\u0443, \u043f\u043e\u0445\u0456\u0434\u043d\u0456 \u0430\u043d\u0456\u043b\u0456\u043d\u043e\u043f\u0456\u0440\u0438\u043c\u0456\u0434\u0438\u043d\u0443, \u043f\u043e\u0445\u0456\u0434\u043d\u0456 \u0431\u0456\u043f\u0438\u0440\u0438\u0434\u0456\u043b\u0456\u044e, \u0440\u043e\u0441\u043b\u0438\u043d\u043d\u0456 \u0432\u0438\u0442\u044f\u0436\u043a\u0438, \u0435\u043a\u0441\u0442\u0440\u0430\u043a\u0442\u0438, \u0445\u0440\u043e\u043c\u0430\u0442\u043e\u0433\u0440\u0430\u0444\u0456\u044f.<\/p>\n

\u0420\u043e\u0437\u0448\u0438\u0440\u0435\u043d\u0430 \u0430\u043d\u043e\u0442\u0430\u0446\u0456\u044f \u0430\u043d\u0433\u043b\u0456\u0439\u0441\u044c\u043a\u043e\u044e \u043c\u043e\u0432\u043e\u044e<\/strong><\/p>\n

Different groups of pesticides are widely used in agriculture to protect oils crops, vegetables and fruits, there are derivatives of benzimidazole, anilinopyrimidine, bipyridylium. The methodology of pesticides control are studying. Optimal conditions of different sample preparation methods and instrumental laboratory control methods were detected. The aim of this study is to examine the different physical and chemical conditions which can be use at practical safety control on the sample preparation procedure for seeds, lettuce leaves and apples fruits. Sample preparation, as a part of laboratory control, have the unique meaning and special importance, contains the multistep endeavour with the expected xenobiotics. The first step on the sample preparation procedure this is sample homogenization, on the next step – xenobiotics extraction using different selective extractants. In this work homogenization of samples was carried out in a glass of a modern mill-homogenizer at a speed of 10000 rev per minute. The obtained homogenized samples due to the difference in its matrix chemical composition and nutritional value had a different aggregate state. Various variations of sample preparation methods were used: extraction by organic liquids (chloroform, acetone, n-hexane, acetonitrile, iso-propanol) and its solutions with mineral and organic acids, extraction by liquids with ultrasound. The general sample preparation scheme was determined and its contains: sample homogenization, plant extraction under the action of selective solvents at ratios 1:5 \u2013 1:20 (raw material-solvent) with the heterogeneous system constant mixing at a speed of 180-200 rev per minute, or under ultrasonic action with a fixed frequency (37 kHz) at a temperature from 4\u00b0\u0421 to 20\u00b0\u0421, on the period 5 – 25 minutes. Plant extracts and analytes extracts was investigated by methods of high-performance liquid chromatography and gas chromatography with both mass-selective detectors which provided the composition control of qualitative and quantitative xenobiotics content.
\nKeywords:<\/strong> safety, xenobiotic, pesticides, derivatives of benzimidazole, derivatives of anilinopyrimidine, derivatives of bipyridylium, plant extracts, extracts, chromatography<\/p>\n

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  14. MacLachlan D. Diquat \/ Dugald MacLachlan \/\/ Specifications for diquat have been developed by FAO. – Australian Government Department of Agriculture, Fisheries and Forestry. \u2013 2008. \u2013 P. 725\u2013803.<\/li>\n
  15. Guidance document on analytical quality control and validation procedures for pesticide residues analysis in food and feed. Document No SANCO\/12495\/2011\u2013 [Implemented by 01\/01\/2014]. \u2013 European Commissionhealth & Consumer Protection Directorate-General \u2013 2013. \u2013 48 p. (Safety of the food chain Chemicals, contaminants, pesticides).<\/li>\n<\/ol>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

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