{"id":1608,"date":"2021-01-16T18:12:39","date_gmt":"2021-01-16T16:12:39","guid":{"rendered":"http:\/\/journals.khnu.km.ua\/vestnik\/?p=1608"},"modified":"2021-05-14T12:26:31","modified_gmt":"2021-05-14T09:26:31","slug":"%d0%b2%d0%b8%d0%ba%d0%be%d1%80%d0%b8%d1%81%d1%82%d0%b0%d0%bd%d0%bd%d1%8f-%d0%bf%d0%b0%d0%ba%d0%b5%d1%82%d1%83-r-%d0%b4%d0%bb%d1%8f-%d0%ba%d0%be%d0%bc%d0%bf%d1%8e%d1%82%d0%b5%d1%80%d0%bd%d0%be%d0%b3","status":"publish","type":"post","link":"https:\/\/journals.khnu.km.ua\/vestnik\/?p=1608","title":{"rendered":"\u0412\u0438\u043a\u043e\u0440\u0438\u0441\u0442\u0430\u043d\u043d\u044f \u043f\u0430\u043a\u0435\u0442\u0443 r \u0434\u043b\u044f \u043a\u043e\u043c\u043f’\u044e\u0442\u0435\u0440\u043d\u043e\u0433\u043e \u043c\u043e\u0434\u0435\u043b\u044e\u0432\u0430\u043d\u043d\u044f \u043a\u043e\u043d\u0442\u0430\u043a\u0442\u0456\u0432 \u0430\u043d\u0442\u0438\u0433\u0435\u043d\u0456\u0432 \u0437 \u0430\u043d\u0442\u0438\u0442\u0456\u043b\u0430\u043c\u0438 \u0432 \u043a\u0456\u0431\u0435\u0440\u0444\u0456\u0437\u0438\u0447\u043d\u0438\u0445 \u0456\u043c\u0443\u043d\u043e\u0441\u0435\u043d\u0441\u043e\u0440\u043d\u0438\u0445 \u0441\u0438\u0441\u0442\u0435\u043c\u0430\u0445 \u043d\u0430 \u043f\u0440\u044f\u043c\u043e\u043a\u0443\u0442\u043d\u0456\u0439 \u0440\u0435\u0448\u0456\u0442\u0446\u0456"},"content":{"rendered":"

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THE USE OF R-PACKAGE R FOR COMPUTER MODELLING OF ANTIGEN CONTACT CONTENTS WITH ANTIBODIES IN CYBER-PHYSICAL IMMUNOSENSOR SYSTEMS ON THE RECTANGLE LATTICE<\/p>\n

<\/a> \u0421\u0442\u043e\u0440\u0456\u043d\u043a\u0438: 97-105. \u041d\u043e\u043c\u0435\u0440: \u21164, 2019 (275)<\/strong>
\n\u0410\u0432\u0442\u043e\u0440\u0438: <\/strong>
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\n\u041d.\u0412. \u041a\u041e\u0417\u041e\u0414\u0406\u0419
\n\u00a0<\/sup>\u0422\u0435\u0440\u043d\u043e\u043f\u0456\u043b\u044c\u0441\u044c\u043a\u0438\u0439 \u043d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u0442\u0435\u0445\u043d\u0456\u0447\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442 \u0456\u043c\u0435\u043d\u0456 \u0406\u0432\u0430\u043d\u0430 \u041f\u0443\u043b\u044e\u044f
\n\u042e.\u0412. \u041a\u0420\u0410\u0412\u0427\u0418\u041a
\n\u0425\u043c\u0435\u043b\u044c\u043d\u0438\u0446\u044c\u043a\u0438\u0439 \u043d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442
\nV.P. MARSENYUK
\nUniversity in Belsko Biala, Poland
\nA.S. SVERSTIUK
\nGorbachevsky Ternopil National Medical University, Ukraine
\nN.V. KOZODII
\nIvan Pul’uj Ternopil National Technical University, Ukraine
\nYU.V. KRAVCHIK
\nKhmelnytsky National University, Ukraine
\nDOI:<\/strong> https:\/\/www.doi.org\/10.31891\/2307-5732-2019-275-4-97-105<\/a>
\n\u0420\u0435\u0446\u0435\u043d\u0437\u0456\u044f\/Peer review :<\/strong> 15.06.2019 \u0440.
\n\u041d\u0430\u0434\u0440\u0443\u043a\u043e\u0432\u0430\u043d\u0430\/Printed :<\/strong> 17.07.2019 \u0440.<\/p>\n

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\n\u041a\u043b\u044e\u0447\u043e\u0432\u0456 \u0441\u043b\u043e\u0432\u0430: <\/strong>\u043a\u0456\u0431\u0435\u0440\u0444\u0456\u0437\u0438\u0447\u043d\u0430 \u0441\u0438\u0441\u0442\u0435\u043c\u0430, \u0431\u0456\u043e\u0441\u0435\u043d\u0441\u043e\u0440, \u0456\u043c\u0443\u043d\u043e\u0441\u0435\u043d\u0441\u043e\u0440, \u043c\u0430\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u043d\u0430 \u043c\u043e\u0434\u0435\u043b\u044c, \u0434\u0438\u0444\u0435\u0440\u0435\u043d\u0446\u0456\u0430\u043b\u044c\u043d\u0456 \u0440\u0456\u0432\u043d\u044f\u043d\u043d\u044f, \u043f\u0430\u043a\u0435\u0442 R.<\/p>\n

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The computer modelling of contacts of antigens with antibodies in cyberphysical immunosensory systems on a rectangular lattice using delayed differential equations with the help of the package is carried out in the work. The subject of the study is a cyberphysical immunosensory system on a rectangular lattice using delayed differential equations. The purpose of this work is to study the contacts of antigens with antibodies of the cyberphysical immunosensory system on a rectangular lattice using delayed differential equations with the help of the packet R. The computer program “Computer simulation of antigen-antibody contacts in cyberphysical immunosensory systems on a rectangular lattice using delayed differential equations” was implemented. The computer modelling of the studied model is carried out, the parameters of the model, their numerical values are given, as well as the parameters in the package R. The latest researches in the field of immunosensors, their types, and the popularity of scientific research areas have been analysed in recent years. Despite the huge variety of modern physic-chemical methods of detecting the analytical signal in immunoassay, electrochemical methods are widely used, with a number of undeniable advantages: high sensitivity and accuracy, selectivity and expressiveness, not high cost and versatility. The package R is described as a programming environment for statistical analysis of data with given values of parameters of a immunosensor model on a rectangular lattice using delayed differential equations. The links to useful sites and guidelines for working with package R. The results of numerical modelling of antibody antigens contacts in cyberphysical immunosensory systems on a rectangular lattice using delayed differential equations allow us to conduct a study of the stability of a model of an immunosensor. It is established that its qualitative behaviour essentially depends on the time of delay.
\nKey words:<\/strong> cyber-physical system, biosensor, immunosensor, mathematical model, differential equations, packet R.<\/p>\n

References<\/strong><\/p>\n

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