{"id":1709,"date":"2021-01-16T18:59:44","date_gmt":"2021-01-16T16:59:44","guid":{"rendered":"http:\/\/journals.khnu.km.ua\/vestnik\/?p=1709"},"modified":"2021-04-19T12:52:34","modified_gmt":"2021-04-19T09:52:34","slug":"%d1%80%d0%be%d0%b7%d1%80%d0%be%d0%b1%d0%ba%d0%b0-%d0%ba%d1%96%d0%b1%d0%b5%d1%80%d1%84%d1%96%d0%b7%d0%b8%d1%87%d0%bd%d0%b8%d1%85-%d0%b1%d1%96%d0%be%d1%81%d0%b5%d0%bd%d1%81%d0%be%d1%80%d0%bd%d0%b8%d1%85","status":"publish","type":"post","link":"https:\/\/journals.khnu.km.ua\/vestnik\/?p=1709","title":{"rendered":"\u0420\u043e\u0437\u0440\u043e\u0431\u043a\u0430 \u043a\u0456\u0431\u0435\u0440\u0444\u0456\u0437\u0438\u0447\u043d\u0438\u0445 \u0431\u0456\u043e\u0441\u0435\u043d\u0441\u043e\u0440\u043d\u0438\u0445 \u0441\u0438\u0441\u0442\u0435\u043c \u0434\u043b\u044f \u043c\u0435\u0434\u0438\u043a\u043e-\u0431\u0456\u043e\u043b\u043e\u0433\u0456\u0447\u043d\u0438\u0445 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u044c"},"content":{"rendered":"

\u0420\u041e\u0417\u0420\u041e\u0411\u041a\u0410 \u041a\u0406\u0411\u0415\u0420\u0424\u0406\u0417\u0418\u0427\u041d\u0418\u0425 \u0411\u0406\u041e\u0421\u0415\u041d\u0421\u041e\u0420\u041d\u0418\u0425 \u0421\u0418\u0421\u0422\u0415\u041c \u0414\u041b\u042f \u041c\u0415\u0414\u0418\u041a\u041e-\u0411\u0406\u041e\u041b\u041e\u0413\u0406\u0427\u041d\u0418\u0425 \u0414\u041e\u0421\u041b\u0406\u0414\u0416\u0415\u041d\u042c<\/p>\n

DEVELOPMENT OF CYBER-PHYSICAL BIOSENSOR SYSTEMS FOR MEDICAL-BIOLOGICAL RESEARCH<\/p>\n

<\/a> \u0421\u0442\u043e\u0440\u0456\u043d\u043a\u0438: 252-257. \u041d\u043e\u043c\u0435\u0440: \u21165, 2019 (277)<\/strong>
\n\u0410\u0432\u0442\u043e\u0440\u0438: <\/strong>
\n\u0410.\u0421. \u0421\u0412\u0415\u0420\u0421\u0422\u042e\u041a, \u041e.\u0410. \u0411\u0410\u0413\u0420\u0406\u0419-\u0417\u0410\u042f\u0426\u042c, \u0410.\u0411. \u0413\u041e\u0420\u041a\u0423\u041d\u0415\u041d\u041a\u041e, \u0417.\u0412. \u041c\u0410\u0419\u0425\u0420\u0423\u041a
\n\u0422\u0435\u0440\u043d\u043e\u043f\u0456\u043b\u044c\u0441\u044c\u043a\u0438\u0439 \u043d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u043c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442 \u0456\u043c\u0435\u043d\u0456 \u0406.\u042f. \u0413\u043e\u0440\u0431\u0430\u0447\u0435\u0432\u0441\u044c\u043a\u043e\u0433\u043e
\n\u041e.\u0412. \u041c\u041e\u0419\u0421\u0415\u0404\u041d\u041a\u041e
\n\u0406\u0432\u0430\u043d\u043e-\u0424\u0440\u0430\u043d\u043a\u0456\u0432\u0441\u044c\u043a\u0438\u0439 \u043d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u043c\u0435\u0434\u0438\u0447\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442
\nA.S. SVERSTIUK, O.A. BAGRIY-ZAYATS, A.B. HORKUNENKO, Z.V. MAYHRUK
\nHorbachevsky Ternopil National Medical University
\nO.V. MOISEIENKO
\nIvano-Frankivsk National Medical University
\nDOI:<\/strong> https:\/\/www.doi.org\/10.31891\/2307-5732-2019-277-5-252-257<\/a>
\n\u0420\u0435\u0446\u0435\u043d\u0437\u0456\u044f\/Peer review :<\/strong> 17.06.2019 \u0440.
\n\u041d\u0430\u0434\u0440\u0443\u043a\u043e\u0432\u0430\u043d\u0430\/Printed :<\/strong> 23.07.2019 \u0440.<\/p>\n

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\n\u041a\u043b\u044e\u0447\u043e\u0432\u0456 \u0441\u043b\u043e\u0432\u0430:<\/strong> \u043a\u0456\u0431\u0435\u0440\u0444\u0456\u0437\u0438\u0447\u043d\u0430 \u0441\u0438\u0441\u0442\u0435\u043c\u0430, \u0431\u0456\u043e\u0441\u0435\u043d\u0441\u043e\u0440, \u0456\u043c\u0443\u043d\u043e\u0441\u0435\u043d\u0441\u043e\u0440, \u043d\u0430\u043d\u043e\u0441\u0435\u043d\u0441\u043e\u0440.<\/p>\n

\u0420\u043e\u0437\u0448\u0438\u0440\u0435\u043d\u0430 \u0430\u043d\u043e\u0442\u0430\u0446\u0456\u044f \u0430\u043d\u0433\u043b\u0456\u0439\u0441\u044c\u043a\u043e\u044e \u043c\u043e\u0432\u043e\u044e<\/strong><\/p>\n

In the work considered promising direction of cyber-physical systems used in medical applications to create highly stable sensor devices based on synthetic analogues of biological receptors, combining high selectivity in recognizing different analytes with high stability inherent in synthetic materials for the hard conditions of storage and use. The systems that can be integrated into various analytical systems and into the human body for continuous monitoring of a number of substances and metabolites are presented. An important method of non-invasive diagnostics and as a direction is described development of modern cyber-physical systems, which does not involve damage to the skin and mucous membranes when sampling for analysis. In the work considered cyber-physical systems and for biomedical research, including portable system for monitoring physiological data mode and real time with dynamic, non-invasive measurement of biochemical markers in biological fluids such as sweat, tears, saliva and interstitial fluid. A cyber physical systems and for biomedical research for complex monitoring of biochemical parameters. A schematic illustration of biosensors of glucose, lactate, sodium, potassium and temperature for multiplex analysis of band flux, including ion-selective electrodes, polyvinyl butyral, glucose oxidase and lactate oxidase. Graphene biosensors that are implanted in the tooth for remote monitoring of respiration and detection of bacteria in saliva are considered. Functional diagram of cyber-physical systems and for biomedical research is presented, as well as the result of numerical simulation of an electrical signal from a converter that characterizes the number of fluorescent pixels
\nKeywords:<\/strong> cyber-physical system, biosensor, immunosensor, nanosensor.<\/p>\n

References<\/strong><\/p>\n

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