{"id":7913,"date":"2021-08-31T18:52:59","date_gmt":"2021-08-31T15:52:59","guid":{"rendered":"http:\/\/journals.khnu.km.ua\/vestnik\/?p=7913"},"modified":"2021-09-29T15:14:19","modified_gmt":"2021-09-29T12:14:19","slug":"syntetychni-barvnyky-v-medyczyni","status":"publish","type":"post","link":"https:\/\/journals.khnu.km.ua\/vestnik\/?p=7913","title":{"rendered":"\u0421\u0438\u043d\u0442\u0435\u0442\u0438\u0447\u043d\u0456 \u0431\u0430\u0440\u0432\u043d\u0438\u043a\u0438 \u0432 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0456"},"content":{"rendered":"<p><!--more--><\/p>\n<p style=\"text-align: center;\">\u0421\u0418\u041d\u0422\u0415\u0422\u0418\u0427\u041d\u0406 \u0411\u0410\u0420\u0412\u041d\u0418\u041a\u0418 \u0412 \u041c\u0415\u0414\u0418\u0426\u0418\u041d\u0406<\/p>\n<p style=\"text-align: center;\">SYNTHETIC DYES IN MEDICINE<\/p>\n<p><strong>\u0421\u0442\u043e\u0440\u0456\u043d\u043a\u0438: 168-172. \u041d\u043e\u043c\u0435\u0440: \u21163, 2021 (297)<\/strong> <a href=\"http:\/\/journals.khnu.km.ua\/vestnik\/wp-content\/uploads\/2021\/08\/27-2.pdf\"> <img loading=\"lazy\" class=\"size-full wp-image-69 alignnone\" src=\"http:\/\/journals.khnu.km.ua\/vestnik\/wp-content\/uploads\/2021\/01\/pdf.png\" alt=\"\" width=\"76\" height=\"32\" \/><\/a><br \/>\n<strong>\u0410\u0432\u0442\u043e\u0440\u0438:<\/strong><br \/>\n\u041e.\u041e. \u0413\u0410\u0420\u0410\u041d\u0406\u041d\u0410, \u042f.\u0412. \u0420\u0415\u0414\u042c\u041a\u041e, \u041c.\u041c. \u041f\u0420\u041e\u0421\u041a\u0423\u0420\u041a\u0410, \u0420.\u042e. \u0412\u0410\u0422\u0410\u041d<br \/>\n\u041a\u0438\u0457\u0432\u0441\u044c\u043a\u0438\u0439 \u043d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0456\u0439 \u0442\u0430 \u0434\u0438\u0437\u0430\u0439\u043d\u0443<br \/>\nO.O. HARANINA, YA.V. RED\u2019KO, M.M. PROSKURKA, R.Y. VATAN<br \/>\nKyiv National University of Technologies and Design<br \/>\n<strong>DOI:<\/strong><a href=\"https:\/\/www.doi.org\/10.31891\/2307-5732-2021-297-3-168-172\">\u00a0https:\/\/www.doi.org\/10.31891\/2307-5732-2021-297-3-168-172<\/a><br \/>\n<strong>\u041d\u0430\u0434\u0456\u0439\u0448\u043b\u0430 \/ Paper received :\u00a0<\/strong> 04.05.2021 \u0440<br \/>\n<strong>\u041d\u0430\u0434\u0440\u0443\u043a\u043e\u0432\u0430\u043d\u0430 \/ Paper Printed : <\/strong>30.06.2021 \u0440<\/p>\n<p style=\"text-align: center;\"><strong>\u0410\u043d\u043e\u0442\u0430\u0446\u0456\u044f \u043c\u043e\u0432\u043e\u044e \u043e\u0440\u0438\u0433\u0456\u043d\u0430\u043b\u0443<\/strong><\/p>\n<p>\u0421\u0438\u043d\u0442\u0435\u0442\u0438\u0447\u043d\u0456 \u0431\u0430\u0440\u0432\u043d\u0438\u043a\u0438 \u0442\u0430 \u043d\u0430\u043f\u0456\u0432\u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438 \u0434\u043b\u044f \u0457\u0445 \u0441\u0438\u043d\u0442\u0435\u0437\u0443 \u043c\u0430\u044e\u0442\u044c \u0448\u0438\u0440\u043e\u043a\u0435 \u0437\u0430\u0441\u0442\u043e\u0441\u0443\u0432\u0430\u043d\u043d\u044f \u043d\u0435 \u0442\u0456\u043b\u044c\u043a\u0438 \u0434\u043b\u044f \u043d\u0430\u0434\u0430\u043d\u043d\u044f \u043a\u043e\u043b\u043e\u0440\u0438\u0441\u0442\u0438\u0447\u043d\u0438\u0445 \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u0435\u0439 \u0442\u0435\u043a\u0441\u0442\u0438\u043b\u044c\u043d\u0438\u043c \u043c\u0430\u0442\u0435\u0440\u0456\u0430\u043b\u0430\u043c, \u0430\u043b\u0435 \u0456 \u0432\u0438\u043a\u043e\u0440\u0438\u0441\u0442\u043e\u0432\u0443\u044e\u0442\u044c\u0441\u044f \u0432 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0456 \u0437\u0430\u0432\u0434\u044f\u043a\u0438 \u0444\u0443\u043d\u043a\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u043c \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u044f\u043c. \u041d\u0430\u0434\u0430\u043d\u043d\u044f \u0442\u0435\u043a\u0441\u0442\u0438\u043b\u044c\u043d\u0438\u043c \u043c\u0430\u0442\u0435\u0440\u0456\u0430\u043b\u0430\u043c \u0431\u0456\u043e\u0446\u0438\u0434\u043d\u0438\u0445 \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u0435\u0439 \u043f\u0440\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u044c \u0434\u043e \u0437\u0430\u0445\u0438\u0441\u0442\u0443 \u043f\u043e\u0432\u0435\u0440\u0445\u043d\u0456 \u043c\u0430\u0442\u0435\u0440\u0456\u0430\u043b\u0443 \u0432\u0456\u0434 \u0434\u0456\u0457 \u043c\u0456\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0456\u0437\u043c\u0456\u0432, \u0430 \u0442\u0430\u043a\u043e\u0436 \u0437\u0430\u0445\u0438\u0449\u0430\u0454 \u043b\u044e\u0434\u0441\u044c\u043a\u0435 \u0442\u0456\u043b\u043e \u0432\u0456\u0434 \u0434\u0456\u0457 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0457 \u043c\u0456\u043a\u0440\u043e\u0444\u043b\u043e\u0440\u0438. \u0412 \u0440\u043e\u0431\u043e\u0442\u0456 \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u043e \u0430\u043d\u0430\u043b\u0456\u0437 \u043d\u0430\u0443\u043a\u043e\u0432\u043e\u0457 \u043b\u0456\u0442\u0435\u0440\u0430\u0442\u0443\u0440\u0438 \u0443 \u0441\u0444\u0435\u0440\u0456 \u0431\u0430\u0440\u0432\u043d\u0438\u043a\u0456\u0432 \u0437 \u0431\u0456\u043e\u0446\u0438\u0434\u043d\u0438\u043c\u0438 \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u044f\u043c\u0438.<br \/>\n<strong>\u041a\u043b\u044e\u0447\u043e\u0432\u0456 \u0441\u043b\u043e\u0432\u0430:<\/strong> \u0441\u0438\u043d\u0442\u0435\u0442\u0438\u0447\u043d\u0456 \u0431\u0430\u0440\u0432\u043d\u0438\u043a\u0438, \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430, \u043a\u043e\u043b\u043e\u0440\u0443\u0432\u0430\u043d\u043d\u044f, \u0430\u043d\u0442\u0438\u0431\u0430\u043a\u0442\u0435\u0440\u0456\u0430\u043b\u044c\u043d\u0456 \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u0456.<\/p>\n<p style=\"text-align: center;\"><strong>\u0420\u043e\u0437\u0448\u0438\u0440\u0435\u043d\u0430 \u0430\u043d\u043e\u0442\u0430\u0446\u0456\u044f \u0430\u043d\u0433\u043b\u0456\u0439\u0441\u044c\u043a\u043e\u044e \u043c\u043e\u0432\u043e\u044e<\/strong><\/p>\n<p>Synthetic dyes and intermediates for their synthesis are widely used in dyeing textile materials. The presence of the necessary functional groups in the structure of the dyes provides their biocidal properties. When using dyes with biocidal properties, the surface of textile materials is seized from destruction. Separate representative dyes protect the human body from the action of pathogenic microflora. It is necessary to create conditions for a timely attack by the textile material on bacteria and fungi. A sufficient number of natural and synthetic compounds exhibit antimicrobial activity. Many of these compounds are hazardous to humans and animals. Only a few chemical compounds can be recommended for practical use as antiseptic preparations. The inclusion of even a small fraction of antibacterial fibers in the structure of textile materials can provide the desired properties.<br \/>\nThe biostability of fibrous materials is influenced by the choice of dye. Not all dyes that have bactericidal activity in their pure form exhibit it when applied to textile material. For the manifestation of these functions, dyes must have groups responsible for their bacteriological activity.<br \/>\nIn developed countries, attempts are being made to uniform dyeing and bioprotective processing of textile materials. The combination of these processes is not only theoretical but also a promising area of \u200b\u200bresearch.<br \/>\nWhen creating antibacterial textile materials, nanotechnology is being actively introduced. The use of nanotechnology reduces the cost of raw materials and materials. At the same time, the most promising for use in medicine are nanomaterials that meet the following requirements, such as biocompatibility and programmability of a positive effect on a biological object.<br \/>\nThus, the article analyzes the scientific literature in the field of dyes with biocidal properties.<\/p>\n<p style=\"text-align: center;\"><strong>References<\/strong><\/p>\n<ol>\n<li>Soldatenkov A.T. Osnovy organicheskoj himii lekarstvennyh preparatov \/ A.T. Soldatenkov, N.M. Kolyadina, I.V. Shendrik. \u2013 M. : Himiya, 2001. \u2013 192 s.<\/li>\n<li>Belikov V.G. Uchebnoe posobie po farmacevticheskoj himii \/ V.G. Belikov. \u2013 Moskva : Medicina, 1979. \u2013 552 s<\/li>\n<li>Laptev N.G. Himiya krasitelej \/ N.G. Laptev, B.M. Bogoslovskij. \u2013 Moskva : Himiya, 1970. \u2013 426 s.<\/li>\n<li>Piccirillo C. Antimicrobial activity of methylene blue and to luidine blue Ocovalently bound to a modified silicone polymer surface \/ C. Piccirillo, S. Perni, J. Gil-Thomas, P. Prokopovich, M. Wilson, J. Pratten, I. P. Parkin \/\/ J. Mater. Chem. \u2013 2009. \u2013 V. 19. \u2013 P. 6167\u20136171<\/li>\n<li>Krasilnikov A. P. Spravochnik po antiseptike \/ A. P. Krasilnikov \/\/ Vysshaya shkola. \u2013 Minsk, 1995. \u2013 367 s.<\/li>\n<li>Venkatarman K. Analiticheskaya himiya sinteticheskih krasitelej \/ Venkatarman K. \u2013 L. : Himiya. \u2013 576 s.<\/li>\n<li>Haleckij A. M. Farmacevticheskaya himiya \/ A. M. Haleckij. \u2013 M. Himiya. 1966. \u2013 751 s.<\/li>\n<li>Razuvaev A.V. Prirodnye antimikrobnye svojstva naturalnyh volokon i vopros ih dopolnitelnoj biocidnoj otdelki \/ A.V. Razuvaev \/\/ Tekstilnaya promyshlennost. \u2013 2011. \u2013 \u2116 5. \u2013 S. 38\u201342.<\/li>\n<li>Peters, R.H. Tekstilnaya himiya. 2 Ochistka tekstilnyh materialov ot zagryaznenij \/ Per. s angl. i red. G.E. Kricheskogo. \u2013 M. : Legkaya industriya, 1973.<\/li>\n<li>Safonov V.V. Himicheskaya tehnologiya otdelochnogo proizvodstva \/ V.V. Safonov. \u2013 M. : MGTU, 2002. \u2013 280 s.<\/li>\n<li>Ibrahim M. A. Awad Synthesis of Some New Azosulphonamides Based on Salicylic Acid and Thiosalicylic Acid, and Having Antibacterial and Antifungal Activity. Dyes and Pigments 1991. P 17. 123\u2013139.<\/li>\n<li>GB 442884, English. Azo compounds and their application and compositions containing the same \/ zayavnik DU PONT; opubl. 17.02.1936<\/li>\n<li>Ali A. Abdel Hafez, Ibrahim M. A. Awad Azo-Dyes Related to 5sulphonylpipiperidino and\/or Morpholino-8-Quinolinol \/\/ Dyes and Pigments. 1992. P. 20. 197\u2013209.<\/li>\n<li>FR 2436161, France. Halogen-containing azo dyes \/ Zayavnik TSNII SCHERSTJANOJ PROMY; opublikovano 11.04.1980.<\/li>\n<li>Rybina I.I. Sintez i issledovanie svojstv proizvodnyh 3,5-dihlorpirid2-ilgidrazina : dis. na soiskanie uchenoj stepeni kand. him. nauk. \u2013 Moskva, 2001. \u2013 158 s.<\/li>\n<li>Kobrakov K.I. Zashita tekstilnyh materialov iz volokon razlichnyh tipov ot biopovrezhdenij s pomoshyu specialnyh krasitelej \/ K.I. Kobrakov, V.T. Kondratkov, G.S. Stankevich, M.B. Dmitrieva \/\/ Himicheskie volokna. \u2013 1999. \u2013 \u2116 4. \u2013 S. 38\u201340.<\/li>\n<li>Rozova Z.S. Vodouporno-gnilostnaya propitka krasheniem \/ Z.S. Rozova \/\/ Tekstilnaya promyshlennost. \u2013 1941. \u2013 \u2116 10. \u2013 S. 20-21.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[51],"tags":[],"_links":{"self":[{"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=\/wp\/v2\/posts\/7913"}],"collection":[{"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7913"}],"version-history":[{"count":4,"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=\/wp\/v2\/posts\/7913\/revisions"}],"predecessor-version":[{"id":8318,"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=\/wp\/v2\/posts\/7913\/revisions\/8318"}],"wp:attachment":[{"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7913"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7913"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/journals.khnu.km.ua\/vestnik\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7913"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}