{"id":8465,"date":"2021-10-25T14:55:27","date_gmt":"2021-10-25T11:55:27","guid":{"rendered":"http:\/\/journals.khnu.km.ua\/vestnik\/?p=8465"},"modified":"2021-11-24T10:00:23","modified_gmt":"2021-11-24T08:00:23","slug":"antymikrobni-vlastyvosti-ligninu-yak-pryrodnogo-bioczydu-dlya-zahystu-tekstylyu","status":"publish","type":"post","link":"https:\/\/journals.khnu.km.ua\/vestnik\/?p=8465","title":{"rendered":"\u0410\u043d\u0442\u0438\u043c\u0456\u043a\u0440\u043e\u0431\u043d\u0456 \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u0456 \u043b\u0456\u0433\u043d\u0456\u043d\u0443 \u044f\u043a \u043f\u0440\u0438\u0440\u043e\u0434\u043d\u043e\u0433\u043e \u0431\u0456\u043e\u0446\u0438\u0434\u0443 \u0434\u043b\u044f \u0437\u0430\u0445\u0438\u0441\u0442\u0443 \u0442\u0435\u043a\u0441\u0442\u0438\u043b\u044e"},"content":{"rendered":"

<\/p>\n

\u0410\u041d\u0422\u0418\u041c\u0406\u041a\u0420\u041e\u0411\u041d\u0406 \u0412\u041b\u0410\u0421\u0422\u0418\u0412\u041e\u0421\u0422\u0406 \u041b\u0406\u0413\u041d\u0406\u041d\u0423 \u042f\u041a \u041f\u0420\u0418\u0420\u041e\u0414\u041d\u041e\u0413\u041e \u0411\u0406\u041e\u0426\u0418\u0414\u0423 \u0414\u041b\u042f \u0417\u0410\u0425\u0418\u0421\u0422\u0423 \u0422\u0415\u041a\u0421\u0422\u0418\u041b\u042e<\/p>\n

ANTIMICROBIAL PROPERTIES OF LIGNINE AS A NATURAL BIOCIDE FOR TEXTILE PROTECTION<\/p>\n

\u0421\u0442\u043e\u0440\u0456\u043d\u043a\u0438: 142-153. \u041d\u043e\u043c\u0435\u0440: \u21164, 2021 (299)<\/strong> \"\"<\/a>
\n\u0410\u0432\u0442\u043e\u0440\u0438:<\/strong>
\n\u0422.\u0410. \u041f\u041e\u041f\u041e\u0412\u0418\u0427
\n\u0425\u0435\u0440\u0441\u043e\u043d\u0441\u044c\u043a\u0438\u0439 \u0434\u0435\u0440\u0436\u0430\u0432\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442
\nORCID: 0000-0001-7449-9949
\n\u0413.\u0412. \u041c\u0406\u0429\u0415\u041d\u041a\u041e
\n\u0425\u0435\u0440\u0441\u043e\u043d\u0441\u044c\u043a\u0438\u0439 \u043d\u0430\u0446\u0456\u043e\u043d\u0430\u043b\u044c\u043d\u0438\u0439 \u0442\u0435\u0445\u043d\u0456\u0447\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442
\nORCID: 0000-0002-0336-1026
\n\u0421.\u041f. \u0411\u0415\u0421\u0427\u0410\u0421\u041d\u0418\u0419
\n\u0425\u0435\u0440\u0441\u043e\u043d\u0441\u044c\u043a\u0438\u0439 \u0434\u0435\u0440\u0436\u0430\u0432\u043d\u0438\u0439 \u0443\u043d\u0456\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442
\nORCID: 0000-0002-7423-4112
\nT.A. POPOVYCH
\nKherson State University
\nORCID: 0000-0001-7449-9949
\nA.V. MISHCHENKO
\nKherson National Technical University
\nORCID: 0000-0002-0336-1026
\nS.P. BESCHASNYI
\nKherson State University
\nORCID: 0000-0002-7423-4112
\nDOI:<\/strong> https:\/\/www.doi.org\/10.31891\/2307-5732-2021-299-4-142-153<\/a>
\n\u0420\u0435\u0446\u0435\u043d\u0437\u0456\u044f\/Peer review :<\/strong> 08.08.2021 \u0440.
\n\u041d\u0430\u0434\u0440\u0443\u043a\u043e\u0432\u0430\u043d\u0430\/Printed :<\/strong> 26.08.2021 \u0440.<\/p>\n

\u0410\u043d\u043e\u0442\u0430\u0446\u0456\u044f \u043c\u043e\u0432\u043e\u044e \u043e\u0440\u0438\u0433\u0456\u043d\u0430\u043b\u0443<\/strong><\/p>\n

\u0410\u043d\u0442\u0438\u0431\u0430\u043a\u0442\u0435\u0440\u0456\u0430\u043b\u044c\u043d\u0430 \u0444\u0443\u043d\u043a\u0446\u0456\u043e\u043d\u0430\u043b\u0456\u0437\u0430\u0446\u0456\u044f \u0454 \u043e\u0434\u043d\u0456\u0454\u044e \u0437 \u0432\u0430\u0436\u043b\u0438\u0432\u0438\u0445 \u0433\u0430\u043b\u0443\u0437\u0435\u0439 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u044c \u0432 \u0442\u0435\u043a\u0441\u0442\u0438\u043b\u044c\u043d\u0456\u0439 \u043f\u0440\u043e\u043c\u0438\u0441\u043b\u043e\u0432\u043e\u0441\u0442\u0456, \u0430\u043b\u0435 \u0442\u0430\u043a\u0456 \u0431\u0456\u043e\u043f\u043e\u043b\u0456\u043c\u0435\u0440\u0438, \u044f\u043a \u043b\u0456\u0433\u043d\u0456\u043d \u0456 \u043f\u0435\u043a\u0442\u0438\u043d, \u0449\u043e \u043c\u0430\u044e\u0442\u044c \u0433\u0430\u0440\u043d\u0443 \u0431\u0456\u043e\u0441\u0443\u043c\u0456\u0441\u043d\u0456\u0441\u0442\u044c, \u0430\u043d\u0442\u0438\u043e\u043a\u0441\u0438\u0434\u0430\u043d\u0442\u043d\u0456 \u0442\u0430 \u0430\u043d\u0442\u0438\u043c\u0456\u043a\u0440\u043e\u0431\u043d\u0456 \u0432\u043b\u0430\u0441\u0442\u0438\u0432\u043e\u0441\u0442\u0456, \u043d\u0430 \u0432\u0456\u0442\u0447\u0438\u0437\u043d\u044f\u043d\u043e\u043c\u0443 \u0440\u0438\u043d\u043a\u0443 \u0437\u0430\u0441\u0442\u043e\u0441\u043e\u0432\u0443\u044e\u0442\u044c\u0441\u044f \u0432 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u043c\u0443 \u0432 \u0431\u0443\u0434\u0456\u0432\u0435\u043b\u044c\u043d\u0456\u0439 \u0442\u0430 \u0445\u0430\u0440\u0447\u043e\u0432\u0456\u0439 \u043f\u0440\u043e\u043c\u0438\u0441\u043b\u043e\u0432\u043e\u0441\u0442\u0456. \u0411\u0443\u043b\u043e \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043e \u0430\u043d\u0442\u0438\u043c\u0456\u043a\u0440\u043e\u0431\u043d\u0443 \u0430\u043a\u0442\u0438\u0432\u043d\u0456\u0441\u0442\u044c \u043d\u0430\u0442\u0440\u0456\u0439 \u043b\u0456\u0433\u043d\u043e\u0441\u0443\u043b\u044c\u0444\u043e\u043d\u0430\u0442\u0443, \u044f\u0431\u043b\u0443\u0447\u043d\u043e\u0433\u043e \u043f\u0435\u043a\u0442\u0438\u043d\u0443 \u0442\u0430 \u0457\u0445 \u0441\u0443\u043c\u0456\u0448\u0456 \u0434\u043e \u0431\u0430\u043a\u0442\u0435\u0440\u0456\u0439 \u0433\u0440\u0430\u043c\u043f\u043e\u0437\u0438\u0442\u0438\u0432\u043d\u0438\u0445 (Staphylococus aureus) \u0456 \u0433\u0440\u0430\u043c\u043d\u0435\u0433\u0430\u0442\u0438\u0432\u043d\u0438\u0445 \u0448\u0442\u0430\u043c\u0456\u0432 (Escherichia coli, Pseudomonas \u0430eruginosa). \u0417\u2032\u044f\u0441\u043e\u0432\u0430\u043d\u043e, \u0449\u043e \u043b\u0456\u0433\u043d\u0456\u043d \u0432 \u043f\u043e\u0440\u0456\u0432\u043d\u044f\u043d\u043d\u0456 \u0437 \u043f\u0435\u043a\u0442\u0438\u043d\u043e\u043c \u043f\u0440\u043e\u044f\u0432\u043b\u044f\u0454 \u0431\u0456\u043b\u044c\u0448\u0443 \u0430\u043d\u0442\u0438\u0431\u0430\u043a\u0442\u0435\u0440\u0456\u0430\u043b\u044c\u043d\u0443 \u0430\u043a\u0442\u0438\u0432\u043d\u0456\u0441\u0442\u044c \u0456 \u043d\u0430\u0439\u0431\u0456\u043b\u044c\u0448 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0438\u0439 \u043f\u0440\u043e\u0442\u0438 \u0431\u0430\u043a\u0442\u0435\u0440\u0456\u0439 Staphylococus aureus. \u041f\u043e\u0441\u0438\u043b\u0435\u043d\u043d\u044f \u0432 2-4 \u0440\u0430\u0437\u0438 \u0430\u043d\u0442\u0438\u0431\u0430\u043a\u0442\u0435\u0440\u0456\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0435\u0444\u0435\u043a\u0442\u0443 \u043f\u043e \u0432\u0456\u0434\u043d\u043e\u0448\u0435\u043d\u043d\u044e \u0434\u043e \u0432\u0441\u0456\u0445 \u043c\u0456\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0456\u0437\u043c\u0456\u0432 \u0441\u043f\u043e\u0441\u0442\u0435\u0440\u0456\u0433\u0430\u043b\u043e\u0441\u044f \u043f\u0440\u0438 \u0441\u0443\u043c\u0456\u0441\u043d\u043e\u043c\u0443 \u0437\u0430\u0441\u0442\u043e\u0441\u0443\u0432\u0430\u043d\u043d\u0456 \u043b\u0456\u0433\u043d\u0456\u043d\u0443 \u0456 \u043f\u0435\u043a\u0442\u0438\u043d\u0443, \u044f\u043a \u0441\u0438\u043d\u0435\u0440\u0433\u0435\u0442\u0438\u0447\u043d\u043e\u0457 \u0441\u0443\u043c\u0456\u0448\u0456. \u0414\u0430\u043d\u0430 \u0440\u043e\u0431\u043e\u0442\u0430 \u043c\u043e\u0436\u0435 \u0431\u0443\u0442\u0438 \u043a\u043e\u0440\u0438\u0441\u043d\u0430 \u043f\u0440\u0438 \u0441\u0442\u0432\u043e\u0440\u0435\u043d\u043d\u0456 \u0430\u043d\u0442\u0438\u043c\u0456\u043a\u0440\u043e\u0431\u043d\u0438\u0445 \u043a\u043e\u043c\u043f\u043e\u0437\u0438\u0446\u0456\u0439 \u0434\u043b\u044f \u0437\u0430\u0445\u0438\u0441\u0442\u0443 \u0442\u0435\u043a\u0441\u0442\u0438\u043b\u044c\u043d\u0438\u0445 \u043c\u0430\u0442\u0435\u0440\u0456\u0430\u043b\u0456\u0432.
\n\u041a\u043b\u044e\u0447\u043e\u0432\u0456 \u0441\u043b\u043e\u0432\u0430:<\/strong> \u0430\u043d\u0442\u0438\u043c\u0456\u043a\u0440\u043e\u0431\u043d\u0456 \u0430\u0433\u0435\u043d\u0442\u0438, \u0430\u043d\u0442\u0438\u043c\u0456\u043a\u0440\u043e\u0431\u043d\u0438\u0439 \u0442\u0435\u043a\u0441\u0442\u0438\u043b\u044c, \u043b\u0456\u0433\u043d\u0456\u043d, \u043f\u0435\u043a\u0442\u0438\u043d.<\/p>\n

\u0420\u043e\u0437\u0448\u0438\u0440\u0435\u043d\u0430 \u0430\u043d\u043e\u0442\u0430\u0446\u0456\u044f \u0430\u043d\u0433\u043b\u0456\u0439\u0441\u044c\u043a\u043e\u044e \u043c\u043e\u0432\u043e\u044e<\/strong><\/p>\n

The functionalization of antibacterial drugs is one of the important areas of research in the textile industry. It uses traditional antimicrobial agents of synthetic or natural origin, and generates new biopolymers with useful properties. Some of them, such as lignin and pectin, have good biocompatibility, antioxidant and antimicrobial properties, but the domestic market uses them mainly in the construction and food industries, respectively.
\nThe antimicrobial activity of sodium lignosulfonate, apple pectin and their mixture against gram-positive bacteria (Staphylococus aureus) and gram-negative strains (Escherichia coli, Pseudomonas aeruginosa) was studied. Experimental results have shown that lignin exhibits slightly higher antibacterial activity compared to pectin and is more effective against Staphylococcus aureus in terms of minimal bactericidal and minimal inhibitory concentrations. Determination of cytotoxicity of sodium lignosulfonate by MTT showed the non-toxicity of this biocide for human cells.
\nIt was found that the antimicrobial behavior of lignosulfonates, pectins and their mixtures differs in relation to gram-positive and gram-negative strains of bacteria. It appeared that the most vulnerable to bactericides are gram-positive strains of Staphylococcus aureus due to the possible absence of double-membrane wall cells.
\nIn addition, the simultaneous use of lignin and pectin as a synergistic mixture showed an increase in antibacterial action against all microorganisms by 2-4 times.
\nThe antimicrobial effect of the studied biocides was compared to the traditional antimicrobial drug argent nitrate, which is widely used in various industries, including textile production. It was found that lignin and pectin in amounts of 1-5 \u043c\u0433\/\u0441\u043c3<\/sup> have the same antimicrobial effect for gram-positive strains and 10-20 \u043c\u0433\/c\u043c3<\/sup> – for gram-negative bacteria, as a solution of AgNO3<\/sub> with a concentration of 0.2 \u043c\u0433\/\u0441\u043c3<\/sup>. Higher concentrations of lignin and pectin can be offset by significantly lower prices compared to argentum salts, as well as greater environmental and medical safety for human health. In addition, lignin is potentially available in large quantities as a by-product from the pulp industry and lignocellulosic bioprocessing plants.
\nThis piece of work may be useful in future when creating antimicrobial compositions for textiles.
\nKeywords:<\/strong> antimicrobials, antimicrobial textiles, lignin, pectin.<\/p>\n

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